Topic: peak negative pressure

Transcranial focused ultrasound (tFUS) is a non-invasive neurostimulation modality capable of targeting deep brain regions with high spatial resolution. Despite its growing popularity, there is still a need to investigate the direct effect of its focused mechanical waves on the activation of the neuronal populations in specific brain areas in addition to the role that each of its physical parameters plays in this process. For this purpose, we have used fluorescent calcium imaging with fiber photometry to visualize the changes in the neuronal activity upon stimulation with tFUS. Fiber photometr