ePoster · Neuroscience
The predictive power of neurological factors for differentiated attention functions in children and adolescents with the genetic disorder neurofibromatosis type 1
Rita Hansl, David Steyrl, Lena Fichtinger, Amedeo Azizi, Ulrike Leiss, Thomas Pletschko · FENS Forum 2024
Neurofibromatosis type 1 (NF1) is one of the most prevalent rare genetic diseases, confronting patients with numerous medical (neurological, cutaneous, osseous) and neuropsychological symptoms. To identify risk factors and allow for targeted neuropsychological intervention, potential associations between the heterogenous somatic and cognitive phenotype have been proposed.The present study harnesses the benefits of machine learning analysis to investigate potential non-/linear associations between the medical and neuropsychological profiles of n=236 pediatric NF1 patients. A total of 14 models