Topic: perfluoroalkyl substances

The increasing environmental spreading of perfluoroalkyl substances (PFASs) raises concerns for theirimpact on human health. PFASs are synthetic chemicals widely used in industrial and consumerproducts to make surfaces repellent to water and lipids. Once ingested or inhaled, PFASs arebioaccumulated in the blood, liver, kidney, and brain of various species with an elimination half-lifein humans of 3-5 years. In a previous publication, we highlighted for the first time that theaccumulation of PFASs can alter the development of human dopaminergic neurons (Di Nisio et al.,2022). This finding, toge