Topic: peri-synaptic astrocytic processes

Astrocytes play an active role in shaping and maintaining neuronal circuits and the blood-brain barrier. In addition to their long-established role in extracellular potassium buffering and glutamate uptake, these cells can also regulate the activity of local synaptic circuits through secretion and clearance of neurotransmitters. Whilst the molecular signal exchange between astroglia and synapses occurs in a highly heterogeneous microenvironment on the nanoscale, the spatial subcellular distribution of the underlying molecular machineries remains poorly understood. Similarly, in addition to clo