Neural stem cells (NSCs) in the adult mouse brain contribute to lifelong brain plasticity. NSCs in the adult ventricular-subventricular zone (V-SVZ) are heterogeneous and, depending on their location in the niche, give rise to different types of olfactory bulb interneurons. We have recently showed that pregnancy activates specific stem cell subpopulations residing in regionally-distinct domains of the niche, with different temporal dynamics. The recruitment of ‘pregnancy-associated’ NSCs is transient, and results in a temporally-controlled generation of different subtypes of olfactory bulb int
ePoster · Neuroscience