Plastic changes of neurons and pericellular synapses in spinal cord after peripheral nerve injury
Katsuyuki Konishi, Toru Iwahashi, Toshiki Shimada, Yoshiaki Yoshimura, Atsushi Kamata, Mai Konishi, Arisa Kazui, Ryoya Shiode, Satoshi Miyamura, Kunihiro Oka, Seiji Okada, Hiroyuki Tanaka · FENS Forum 2024
Aims: Plastic changes of neurons in spinal cord after peripheral nerve injury remain to be elucidated. The aim of this research is to clarify plastic changes of neurons and pericellular synapses in lumbar spinal cord after sciatic nerve transection.Methods: Neurons and pericellular synapses in lumbar spinal cord of rats were analyzed 6 weeks after sciatic nerve transection. The axonal volume of cortical neurons was labeled with biotinylated dextran amine, the volume of motoneuron soma with Fluoro-Gold, cholinergic interneurons with vAchT, and pericellular synapses with vGlut1 and vAchT. They w
ePoster · Neuroscience