P. gingivalis and titanium oxide nanoparticles induce inflammation in BBB microglia in vitro
Yasmin Louzon, Rinat Tzach-Nachman, Yael Houri-Haddad · FENS Forum 2024
Research has extensively explored the influence of Periodontitis on Alzheimer’s disease (AD), identifying its role in accelerating the disease via systemic inflammation and bacterial invasion to the brain. Additionally, investigations into titanium oxide nanoparticles (Ti NP) and AD have shown significant effects on cognitive ability in vitro and in vivo. This study aims to assess the synergistic impact of Ti NP and P. gingivalis (Pg), factors involved in periimplantitis pathogenesis, on the neuroinflammatory response of mouse microglia cells (BV2) in vitro.Using a BV2 and RAW (separate contro
ePoster · Neuroscience