Topic: periodic synchronous bursts

Neurological disorders, such as Parkinson’s disease, epilepsy and dystonia, are associated with excessive neuronal activity synchrony that overshadows normal brain activity. To disrupt these pathological occurrences, implantable brain stimulators apply electrical stimulation continuously, in an open-loop setting. However, stimulation should ideally be provided only when needed, guided by a closed-loop control system. Computational studies have focused on developing closed-loop stimulation protocols to counteract excessive neuronal synchronization. Delayed feedback control (DFC) is a method kn