Circuit mechanisms underlying the sexual dimorphic effects of restraint stress on prefrontal cortical neuronal properties
Angeliki Velli, Chrysoula Iordanidou, Kiki Sidiropoulou · FENS Forum 2024
The stress response is a significant precipitating factor in various psychiatric disorders. Numerous neuropsychiatric disorders are characterized by sex differences in the prevalence, type, and severity of symptoms, which include cognitive dysfunctions mainly supported by the prefrontal cortex (PFC). This study aims to evaluate the sexual dimorphic effects of acute stress on PFC synaptic properties, as well as on both the intrinsic and synaptic properties of PFC-basolateral amygdala (BLA) and PFC-PFC projection neurons. Adult male and female mice were exposed to either restraint stress (RS) or
ePoster · Neuroscience