Topic: Phase Lag Index

Network hyperexcitability in Alzheimer’s Disease (AD) is claimed to be an important and potentially treatable pathophysiological mechanism. Empirical and modeling studies suggest that functional connectivity (FC) are promising quantitative neurophysiological markers for network hyperexcitability. This study examines how robust FC measures differ between AD patients with and without interictal epileptiform discharges (IEDs). We obtained eyes closed source-level magnetoencephalography recordings from demographically matched biomarker confirmed AD patients in the mild cognitive impairment and dem