Topic: phosphoproteomic screening

For the nervous system to function properly, mature neurons must have a stable dendritic architecture. Mature neurons still possess the capacity for structural plasticity, which is necessary to facilitate adaptive processes such as memory formation. What molecular and cellular mechanisms regulate this fine balance between dendritic structural stabilization and plasticity is unknown. Aberrant connectivity is the consequence of atrophy or maladaptive plasticity, which fails to preserve the ideal dendritic structure and is linked to a number of neurological disorders. The upkeep of mature dendrit