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Topic: photothrombotic ischemic lesion

ePoster
1 ePoster

In Behavioral Neuroscience and Biology

ePoster · Electrophysiology

Pathological delta oscillation in the subthalamic nucleus of rats with acute stroke relates to motor disability

Zhengdao Deng, Ugur Kilic, Myles Mc Laughlin, Nuttin Bart · FENS Forum 2024

Objectives: We aim to investigate the impact of acute stroke on delta oscillation in STN and to explore the correlation between motor disability and the altered delta oscillation in STN following stroke. Methods: 10 Sprague-Dawley rat were included in this study. They were trained in single pellet reaching task before stroke induction and motor performance was determined as baseline. STN was recorded before and 30 mins within after stroke. A photothrombotic ischemic lesion ipsilateral to the STN recording site was induced in M1. 3 days after the stroke, we evaluated motor performance using t