Topic: photothrombotic stroke model

Stroke is currently the second leading cause of death worldwide, and it accounts for approximately 3-7% of total healthcare expenditures worldwide. Cerebral ischemic stroke has known to cause irreversible damage to the brain by variety mechanisms of excitotoxicity and apoptosis within hours after hypoxic challenge. Recent evidence suggests that a ketogenic diet may reduce infarct volume and neuronal damage in ischemic stroke models. However, the connection between physiological changes induced by the diet with the pathological alterations in hypoxic susceptibility remains unclear. In this rese