Topic: PI3K activator

Traumatic brain injury (TBI) is one of the leading causes for death or disability involving an initial mechanical damage that leads to the destruction of the brain matter and adjacent vasculature, producing a lesion cavity. The treatment options are limited to stabilizing the patients and treating secondary symptoms. Those secondary injuries appear in a time-shifted manner and include axonal injury leading to neuronal death, a process not fully understood yet. For several central nervous system (CNS) injury models including spinal cord injury, it was already shown that the growth factor-activa