Topic: place-cells

Creating internal representations of the surrounding context and stabilizing them are essential for safe exploration of the environment. Spatial memories in the dorsal hippocampus (dHPC) are initially encoded by place-cells during awake exploration and stabilized during non-REM sleep fast oscillations (sharp-wave ripples) through place cell reactivation. The hippocampal formation is heterogeneous; the dHPC processes mostly contextual information, while the ventral part (vHPC) encodes valence and anxiety. This functional segregation is supported by the stronger connectivity of the vHPC with oth