Changes in autonomic nervous system function following administration of probiotics in mild Alzheimer’s patients
Stella Angeli, Ioanna Kousiappa, Stelios Georgiades, Savvas Papacostas, Andreas Koupparis, Yiolanda Christou, Archontia Adamou, Benson Botchway, George Loucaides, Gavriella Alexandrou, Stavros Bashiardes, Andreas Hadjisavvas, Michail Panagiotidis, Aleksandar Jovanovic, Nicoletta Nicolaou · FENS Forum 2024
The gut microbiome plays an integral part in neurodegeneration through its direct interaction with the autonomic nervous system (ANS) via the vagal nerve. The aim of this pilot study is to investigate changes in ANS function in patients with mild Alzheimer’s Disease (AD) following administration of probiotics, compared to placebo (no active probiotics). Patients with mild AD (MMSE: 19-23) who fulfil all eligibility criteria were enrolled on the study and randomly assigned to take probiotics or placebo (control) for 16 weeks. We collected various data at baseline and study completion (weeks 0 &
ePoster · Neuroscience