Topic: polymersomes

Available treatments for brain disorders are commonly pharmacological in nature. Yet, the efficacy and the risk/benefit ratio of brain therapeutics -when they exist- are often dampened by the selectivity of the blood-brain barrier and off-target actions of the molecules, at the periphery as well as in the brain. To improve the efficacy of therapeutic molecules for the brain, their loading in polymersomes (synthetic polymer vesicles) represents a promising strategy due to their high stability, versatility and ability to transport drugs with high efficiency. However, encapsulation does not allow