Development of toroidal and ring manifolds in the entorhinal networks
Matteo Guardamagna, Erik Hermansen, Jordan Carpenter, Christine Marie Lykken, Benjamin Adric Dunn, May-Britt Moser, Edvard Ingjald Moser · FENS Forum 2024
The entorhinal cortex is a crucial hub for the coding of animals’ experiences in space. Grid cells, key components of this network, exhibit multiple firing fields that tessellate the environment as a function of the animals’ location. At the population level, the dynamics of the grid cell network reside on a toroidal manifold, irrespective of the sensory inputs or behavioral state, in agreement with continuous attractor networks (CAN) theories.However, the developmental origin of toroidal topology remains to be determined. Using Neuropixels 2.0 we obtained high-density population recordings in
ePoster · Neuroscience