Topic: preparation subspace

Voluntary movement is often prepared by motor cortex before its execution. Motor cortical neurons exhibit preparatory-activity, a neural correlate of upcoming movement [1]. Animals adopt different behavioral strategies in response to uncertainties existing in nature such as environmental cue informing ‘go’ [2]. However, how motor cortical circuits cope with such uncertainty while benefiting from explicit information is less understood. Here, we analyzed firing activity of anterolateral motor cortex (ALM) while mice performed one of the two different auditory delayed-response tasks: random or f