Topic: primate prefrontal cortex

Representational geometry is a prevalent approach to abstract and investigate population coding derived from the activities of individual neurons. However, the same representational geometry can be implemented by neurons in different ways, which implies different potential readout mechanisms. Leveraging the biological constraint of sparsity of readout synapses, we identified the biologically meaningful sparse components that express the geometry of working memory representations in primate prefrontal cortex (PFC). The dominant neuron groups corresponding to each component had distinct electrop