Changes of Nlrp3 inflammasome regulation in the frontal cortex induced by voluntary wheel running in ovariectomized female adult mice
Konstancja Grabowska, Mateusz Grabowski, Julia Morys, Magdalena Kostka, Jarosław Jerzy Barski, Marta Nowacka-Chmielewska · FENS Forum 2024
Estrogens regulate a variety of processes in the central nervous system (CNS), including inflammatory responses. Therefore, postmenopause, a hypoestrogenic state, may contribute to an increased risk of developing neuroinflammatory-related disorders. Thus, it is proposed to introduce lifestyle changes that could have beneficial effects on the CNS. Regular, moderate physical activity is being considered as a potential intervention for preventing disruption of the neuroinflammation process. The aim was to investigate the impact of voluntary wheel running on neuroinflammation, including Nlrp3 infl
ePoster · Neuroscience