Topic: probabilistic encoder model

Recent studies have shown that behavioral information is richly distributed across the brain, but how individual neurons across the brain encode behavior is largely unknown. However, it is challenging to record/interpret high quality single neuron traces across the brain. Here, we describe new hardware/software and analytical tools to address this. We engineered a microscope to record brain-wide activity and behavior of freely-moving C. elegans, wrote new image analysis software, and developed a probabilistic encoder model to delineate how each neuron encodes specific behavioral features. Extr