Topic: PV-Basket

The mammalian cortex is complex, consisting of many functionally distinct areas. Understanding how this diversification occurs remains a major goal. Interneurons in the adult mouse cortex are diverse, they can be defined based on developmental origin, distinct morphology, physiological and molecular properties (e.g. parvalbumin-expressing basket cells). Despite making up approximately 1/6 of the total neuronal population we do not currently have a cortex-wide map of interneurons.Using transgenic mice to label cells we have mapped the distribution of all interneurons, of 2 broad populations (MG