Inhibitory brain dynamics for adaptive behaviour: The role of GABAergic neurotransmission in orientation discrimination-based visual perceptual learning
Matthew Bailey, Olivia Stupart, Clara Velazquez-Sanchez, Livia Wilod Versprille, Harry Robson, Johann du Hoffmann, Zoe Kourtzi, Jeffrey Dalley · FENS Forum 2024
Gamma-aminobutyric acid (GABA) plays a key role in learning and brain plasticity by regulating functional connectivity and oscillatory activity in local circuits and global brain networks. Altered cortical inhibition is associated with perceptual and learning impairments in psychiatric disorders such as schizophrenia. Despite the importance of GABAergic inhibition for brain function, we lack a mechanistic understanding of the inhibitory network dynamics that support adaptive behaviour from training. To unravel these mechanisms, we developed a progressive 3-stimuli touchscreen orientation discr
ePoster · Neuroscience