ePoster · Developmental Neuroscience
The asymmetric brain: Utilizing hyper-gravity to manipulate developmental symmetries
Felix Graf, Robin Hiesinger · FENS Forum 2024
The evolution and development of all organisms on earth relies on near-constant gravity. Experimental manipulations can create developmental conditions that have never been encountered during evolution, yet reveal developmental mechanisms based on informative phenotypic outcomes; classically, such experiments include transplantation of developing organs as well as pushing boundaries of environmental conditions.Here, we explore the outcome of Drosophila melanogaster brain development at hyper-gravity 10^2 to 10^3 times greater than conventional gravity on earth. Remarkably, Drosophila pupae ful