Topic: RCaMP

Astrocytes are crucial mediators of brain function on a multimodal level such as energy metabolism or synapse formation and maturation. They form a vast network in the brain and signal both with each other and with neurons. Calcium is the primary information carrier in astrocytes and can be measured using fluorescent indicators. Therapeutic approaches for cognitive diseases are commonly designed to influence neurons, but neglect astrocytes, despite them accounting for half the mass of the brain.Here we use astrocytic calcium signals and recent advances in analysis to develop an astrocytic comp