Differential computations across multiple brain regions underlying dexterous movements
Ahmet Arac, Sanjay Shukla, Erica Nagase, Alan Yao, Nicolas Jeong Lee, Kate Santoso, Emily Stenzler, Kasey Kim, David Lipkin, Angela Kan, Christina Abdishoo · COSYNE 2025
Complex dexterous movements, such as reach-and-grasp, are driven by the coordinated activity of multiple brain regions. Each region contributes unique computations while interacting with others to control the movements. To understand the neural principles underlying this behavior across different brain regions, we recorded spiking activity in 10 brain regions while the mice performed a skilled reach-and-grasp task. We identified distinct behavioral phases, each with unique kinematic features. Single neuron analyses showed similar response percentages, with differing response strengths, across
ePoster · Neuroscience