Topic: Regenerative Therapy

Our study investigates the potential synergistic effect of regenerative therapy combining electrical stimulation with application of anti-inflammatory drug atorvastatin (ATR) following spinal cord injury (SCI). Using an isoflurane anesthesia, we induced SCI at the T9 segment with a compression device for 15 minutes under a 40g weight. An oscillating field stimulator (OFS) implanted subcutaneously delivered a weak electric current (50 µA), alternating polarity every 15 minutes for 6 weeks to encourage axonal growth from the lesion site. Wistar albino female rats were randomly divided to four gr