Phenotyping of aging Sprague-Dawley rats: Exploring the relationship between social behavior and locomotor activity
Jovana Aranđelović, Jana Ivanović, Kristina Mirković, Anja Santrač, Miroslav Savić · FENS Forum 2024
Aims: The aging process inevitably influences social behavior and cognition. However, a proportion of the population may resist these changes due to superaging associated with increased movement speed. Therefore, we aimed to phenotype aging animals based on their activity and determine the relationship between locomotor function and social behavior in aging rats.Methods: In 3- and 14-month-old Sprague-Dawley rats, social interaction, memory and locomotion were characterized using resident-intruder test (RIT), social recognition test (SRT) and open-field test, respectively. Animal phenotyping w
ePoster · Neuroscience