Influence of neuromodulators on brain state transitions in larval zebrafish
Antoine Légaré, Sandrine Poulin, Vincent Boily, Mado Lemieux, Patrick Desrosiers, Paul De Koninck · COSYNE 2023
With the rapid growth of optical imaging technologies, the simultaneous observation of brain-wide activity and behavior in small organisms offers a unique opportunity to study how distributed neuronal networks interact to process sensory information and generate behavior. While neuromodulators have been shown to grant flexible state-switching mechanisms to circuits, their influence on global network dynamics is poorly characterized. Using resonant-scanning two-photon microscopy, we measured brain-wide calcium dynamics in head-restrained larval zebrafish while monitoring tail movements to inves
Fri, Mar 10, 2023