Autistic traits mediate the relationship between occipital GABA and perceptual choice in a target detection task
Nazia Jassim, Frederike H Petzschner, Catarina Rua, Simon Baron-Cohen, John Suckling, Rebecca P Lawson · FENS Forum 2024
Inhibitory neurotransmitter GABA is known to play a critical role in perception, yet has been under-explored in humans. Understanding the mechanisms of visual perception is of particular relevance to conditions such as autism spectrum conditions, where differences in sensory perception are a core feature. Here we exploit the high resolution of 7-Tesla Magnetic Resonance Spectroscopy (MRS) to investigate the links between occipital GABA, autistic traits, and perceptual choice in humans. 45 participants (22 Female: 23 Male), aged 19-39 years, completed the Autism Spectrum Quotient questionnaire
ePoster · Neuroscience