ePoster · Behavioral Neuroscience
Prefrontal orchestration: Cortical networks for rodent action control
Zoe Jäckel, Niels Schwaderlapp, Ahmed Adzemovic, Florian Steenbergen, Maxim Zaitsev, Ilka Diester · FENS Forum 2024
Goal-directed action control relies on the prefrontal cortex (PFC), where distinct subsections collaborate in functional networks. The extent to which the network favors a hierarchical system, characterized by early convergence within the PFC, versus a shallow brain hypothesis, featuring numerous parallel circuits from the cortex to downstream targets, remains elusive (Suzuki et al. 2023). Employing optogenetic modulation, behavioral assessments, and fMRI, we investigate the impact of PFC subarea-stimulation on motor control and whole-brain activation patterns. We quantified error rate and rea