The effects of associative learning on neuronal activity and functional connections in the mouse brain resting state networks
Ksenia Toropova, Olga Ivashkina, Anna Ivanova, Konstantin Anokhin · FENS Forum 2024
This study explores the impact of past experiences on resting state brain networks in animals, particularly focusing on the difference between naive mice and those subjected to contextual fear conditioning. We analyzed the resting activity of 41 brain regions, observing significant changes in brain activity 24 hours post-learning. Mice with associative learning experience showed a notable increase in c-Fos-positive cells in specific brain areas known for their role in fear memory formation, such as the prelimbic, retrosplenial, and temporal associative cortex, alongside various amygdala nuclei
ePoster · Neuroscience