Topic: retinal mosaics

The output of the retina is carried by retinal ganglion cells (RGCs) along parallel functional pathways to multiple areas distributed across the vertebrate brain. The functional organization of the synaptic connections between RGCs and their postsynaptic target neurons is largely unknown. Here, we discovered that high-density Neuropixels probes allow the measurement of large populations of RGC axons where they form synaptic contacts, in vivo. The electrophysiological signature of RGC afferent inputs is made of a triphasic waveform composed of the axonal action potential, the axonal terminal re