Topic: retinal neural circuit wiring

During development, the specificity of retinal neural circuit wiring is established by developmental programs that require cell adhesion molecules (CAMs) to define precise layering and connectivity. However, our current understanding of this process remains superficial, as the field has been guided primarily by gross anatomical phenotypes that can be visually quantified. Here, we present an alternative approach to studying circuit wiring that focuses on functional changes rather than relying on morphological ones. To this end, we use the mouse retina as a model and employ a recently developed