Single-cell precision of axonal projection from the retina to the superior colliculus in mice
Hiroki Asari · COSYNE 2023
Retinotopy is generally preserved across the visual system, but its cellular-level organization remains elusive. How precisely is topographic information transmitted from the retina? To address this question, here we combined experimental and computational modelling approaches. First, using two-photon calcium imaging of retinal ganglion cell (RGC) axons as well as local neurons in the superior colliculus (SC), we performed functional mapping of the retinocollicular projection at a single-cell resolution in awake mice. The tiling patterns of RGC axon terminals and their corresponding receptive
Sun, Mar 12, 2023