Feedforward thalamocortical inputs to primary visual cortex are OFF dominant
Jun Zhuang,Naveen Ouellette,R. Clay Reid · COSYNE 2022
The responses of mammalian visual system to the increment (ON) and decrement (OFF) of light are asymmetrical. Previous studies have shown that the OFF responses in early visual systems of higher mammals are dominant. Recently, the OFF dominance had been shown in mouse primary visual cortex (V1), but it is unclear whether the feedforward inputs from dorsal lateral geniculate nucleus (dLGN) to V1 in mouse are OFF dominant. Here, we labeled thalamocortical projecting cells in dLGN with calcium indicator and imaged their axonal bouton activity at different depths in V1. By using locally sparse noi
Sat, Mar 19, 2022