Topic: ROInet-seq

Neuronal networks are at the core of the brain's vast computational capacities. Different strategies have each brought deep insights into their architecture. Yet, each method is limited in its capacity to resolve even simple subnetworks of single cells, due to the current compromise between throughput, resolution, and coverage. Viral projection tracing helps establish regional connectomes of mammalian brains. In combination with additional modification, the method can reveal cell-type-specific projection patterns. However, these maps lack single-neuron resolution. Monosynaptic connectivity tra