Investigating the effect of meropenem on neurogenesis in adult rats
Maram Chaaban, Tamara Fahs, Alaa El Makkawi, Rim Jaber, Nayef Saadeh, Wassim Abou-Kheir · FENS Forum 2024
Neurogenesis is the process where neural stem cells (NSCs) develop into functional neurons. It comprises proliferation, differentiation, migration, axonal and dendritic targeting, and synaptic integration. Meropenem is a broad-spectrum carbapenem that treats various infections. It can penetrate most body fluids and tissues, cross the blood–brain barrier, and obtain a concentration within the cerebrospinal fluid close to that of blood plasma. However, no research has established a link between meropenem and neurotoxic effects on the brain and the subsequent behavioral activity. This project aim
ePoster · Neuroscience