Topic: rule-guided behaviour

Lesion studies have elucidated the distinct roles played by different areas in the prefrontal cortex (PFC) in guiding behaviour according to abstract rules, as observed in a macaque-adapted version of the Wisconsin Card Sorting Test (WCST). Nevertheless, we do not fully understand how these functional specialisations relate to the underlying neuronal activity across these different prefrontal regions. In this study, we present novel insights derived from our multi-area multi-electrode recording in non-human primates (NHPs). We chronically implanted Utah arrays in dorsolateral PFC, ventrolatera