Sweet fat: A recipe for brain fog. Dietary fat and sugar impair cognitive functions in mice
Jakub Chwastek, Piotr Bartochowski, Bartosz Zglinicki, Olga Pietrzyk, Julio C. Torres, Anna Konopka, Marek Kochańczyk, Ewa Bulska, Anna Kiryk, Witold Konopka · FENS Forum 2024
Developed country diets rich in sugar and fat contribute to obesity by affecting both peripheral organs and the brain's appetite regulation. We assessed how diet composition impacts mice's body mass, cognitive function, and metabolism. Our goal was to investigate how diet affects learning in mice and identify potential brain-regulating metabolites. Mice were fed four diets: standard diet (STAND), high-sugar & high-fat diet (HSD), high-fat diet (HFD), ketogenic diet (KD), and mouse weight and food intake were measured weekly. After 8 weeks of dietary feeding, the IntelliCage system was used
ePoster · Neuroscience