Topic: sensorimotor axis

Decisions are often guided by detecting subtle signals in a dynamic sensory environment. Although the brain must track such decision-relevant signals, how they are represented and transformed by neural activity across the sensorimotor axis remains poorly understood. Here, we recorded neural activity with Neuropixels probes across dozens of brain regions while mice performed a visual change-detection task. We trained mice to detect a sustained increase in temporal-frequency (TF) of a drifting grating stimulus, whose speed fluctuates stochastically around the mean of 1Hz. The task requires mice