Topic: serotonergic neuromodulation

During naturalistic foraging, animals deploy complex decision-making strategies to acquire resources in the presence of uncertain environments. Here we focus on a probabilistic foraging task and how serotonergic (5-HT) neuromodulation affects mouse performance via optogenetic activation of the Dorsal Raphae nucleus (DRN). We show that it is necessary to account for the complexity of behavioral variability across mice in order to uncover the strategies mice deploy to perform the task and how serotonergic neuromodulation affects behavior. While most studies have quantified decision-making perfor