Topic: serotonergic nuclei

The Dorsal Raphe Nucleus (DRN) is the largest of the serotonergic nuclei, but it also comprises a wide variety of neuronal subpopulations, including dopaminergic cells (DRNDA) and astrocytes, which may represent a source of local DRN modulation. The DRN participates in a wide range of behavioral responses related to the processing of aversive stimuli, leading to anxiety state. While the role of DRN5-HT and DRNDA in valence processing is emerging, the contribution of DRN astrocytes (DRNAstro), as well as the underpinning cellular mechanisms, remain elusive. Unpublished data from the lab indicat