Topic: sharp wave ripple complexes

The hippocampus is crucial for episodic memories and is characterized by unique sharp wave ripple complexes (SWRs). These hallmark oscillations, 150-250 Hz in the local field potential (LFP), are produced by fast signaling between synaptically coupled pyramidal neurons (PNs) and parvalbumin-positive basket cells (PV+BCs). Although much has been learned about the synaptic and microcircuit properties mediating ripple oscillations, whether and how myelination of the hippocampus contributes remains unresolved. Here, we performed LFP measurements in combination with paired recordings between PV+BCs