Motor arrest by stimulation of the pedunculopontine nucleus disrupts perception of visual cue in a visuospatial cue task
Madelaine Christine Adamsson Bonfils, Silas Dalum Larsen, Jakob F. Sørensen, Rune W. Berg · FENS Forum 2024
The Pedunculopontine nucleus (PPN) has long been associated with locomotion as part of themesencephalic locomotor region, and in arousal and sleep/wake states as part of theascending reticular activating system. In addition, several studies indicate that the PPN isinvolved in several other functions such as path integration, visual and auditory processing,attention and action-selection. As it was recently discovered thatoptogenetic stimulation of the rostral PPN can induce full body motor arrest, we wanted to investigateif this behavior was limited to motor output, or if sensory input was halt
ePoster · Neuroscience