Solid-state nanopores for spatially resolved chemical neuromodulation
Francesca Vacca, Filippo Galluzzi, Maria Blanco-Formoso, Tomaso Gianiorio, Angela F. De Fazio, Sophie Stuermer, Wadood Haq, Eberhart Zrenner, Fabio Benfenati, Francesco De Angelis, Elisabetta Colombo · FENS Forum 2024
Electrical-based neuroprostheses reported promising clinical outcomes for the treatment of neurological disorders. Nevertheless, they suffer from low spatial resolution and lack of natural neurotransmission specificity that require alternative bio-mimetic stimulation strategies. Chemical-based neuroprostheses would represent a promising option to emulate the physiological synaptic communication by providing localized delivery of neurotransmitters. While various drug delivery approaches have been investigated, an efficient neurotransmitter-based neuronal stimulation at the nanoscale still remai
ePoster · Neuroscience