To pave the silk road: A functionalized microvasculature network for the blood-brain interface
Ciro De Luca, Assunta Virtuoso, Giovanni Cirillo, Atocha Guedán, Tando Maduna, Yasin Ilgaz, Alan Morin, Julia Sepulveda Diaz, Andreas Vlachos, Fivos Panetsos, José Pérez-Rigueiro, Michele Papa · FENS Forum 2024
A functional microvasculature is a paramount target for accomplishing long-lasting engineered tissues. The challenge in neuroscience is building a microvascular network that could mimic the neurovascular unit, allowing the central nervous system (CNS) vitality. The vessels invade the CNS extracellular matrix (ECM) during embryogenesis. Biomaterials can offer the structural guidance and signaling pathways to recapitulate this complex process. Our project (THOR – European Innovation Council-Pathfinder Programme, Grant Agreement number 101099719) uses high-performance functionalized silk fibers w
ePoster · Neuroscience