Topic: Single Cell Genomics

A Keystone Symposium bringing together single-cell genomics, spatial biology, perturbation technologies, computational methods, and clinical translation across high-burden diseases.

The Laboratory of Exercise and Health seeks a bioinformatician to lead single-cell and spatial genomics analysis of human and mouse skeletal muscle. Research examines communication between vascular endothelial populations and neighbouring cells, including its disruption in disease. Responsibilities include cell-type annotation, integration of transcriptomic and other omics data, cross-species comparisons, CRISPR-screen analysis, cell-communication and metabolic modelling, and reproducible analysis pipelines. The role works closely with experimental researchers and contributes visualisation, ma

Postdoctoral research with Stefanie Grosswendt’s group at the Max Planck Institute for Molecular Biomedicine, Münster, Germany. The laboratory investigates how neighbouring cells communicate and how these interactions influence gene regulation, cell fate and tissue function. Experimental and computational approaches combine single-cell genomics, CellMate-seq ligand–receptor measurements and imaging-based spatial transcriptomics. Projects examine neural crest development in mouse embryos and neuroblastoma, with complex in-vitro systems and bottom-up reconstruction used to connect communication

The Dorrity group at EMBL Heidelberg seeks a Laboratory Officer to investigate gene regulation and cellular identity with single-cell genomics. Work includes mammalian cell culture and engineering, adapting low-input RNA-sequencing protocols, sequencing-library preparation, CRISPR experiments and laboratory training and management. The three-year, full-time position is based on campus. The advert gives a closing date of 30 September 2026 at 23:59 CET.

Ai2 is recruiting a postdoctoral Young Investigator for CellOLMo, a collaboration using open language models with single-cell brain data. The researcher will develop multimodal models that combine gene-expression data and text, evaluate biological language grounding on the SEA-AD Alzheimer's disease atlas, build donor- and brain-region-level representations, and release resulting models, code, data, and research artifacts openly.

Computational biologist analyzing large-scale perturbational and single-cell datasets, with two tracks available: Perturb-seq/functional genomics or neurobiology/microglia research, supporting major Arc Institute research initiatives.

The symposium will start with Prof Song-Hai Shi who will present “Assembly of the neocortex”. Then, Dr Lynette Lim will talk about “Shared and Unique Developmental Trajectories of Cortical Inhibitory Neurons”. Dr Alfredo Molina will deal with the “Tuneable progenitor cells to build the cerebral cortex”, and Prof Tomasz Nowakowski will present “Charting the molecular 'protomap' of the human cerebral cortex using single cell genomic”.