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Topic: Single nucleus RNA-sequencing

ePoster
1 ePoster

In Neuroscience

Identification of a subpopulation of neurons in the brainstem pons whose activation increases NREM sleep

Ami Kaneko, Mitsuaki Kashiwagi, Mika Kanuka, Gen-ichi Tasaka, Kazunari Miyamichi, Masashi Yanagisawa, Haruka Ozaki, Yu Hayashi · FENS Forum 2024

Sleep is a critical factor that affects overall health, and humans typically spend one-third of their lives sleeping. Sleep consists of two states: rapid eye movement (REM) sleep and non-REM (NREM) sleep. The brainstem pontine tegmental area contains neurons that either positively or negatively regulate REM sleep (Vanni-Mercier et al., 1989; Lu et al., 2006; Hayashi et al., 2015; Kashiwagi et al., 2020). Additionally, some neurons in this area regulate urination (Hou et al., 2016; Keller et al., 2018) and fear (Yang et al., 2016). Thus, the pontine tegmental area consists of multiple subpopula

ePoster · Neuroscience